Urology Research & Practice
Original Article

Overview of different scoring systems in Fournier’s Gangrene and assessment of prognostic factors

1.

Clinic of Urology, Ankara Training and Research Hospital, Ankara, Turkey

2.

Department of Urology, Afyon Kocatepe University School of Medicine, Afyonkarahisar, Turkey

3.

Department of Urology, Hacettepe University School of Medicine, Ankara, Turkey

Urol Res Pract 2016; 42: 190-196
DOI: 10.5152/tud.2016.14194
Read: 1692 Downloads: 1072 Published: 25 July 2019

Abstract

Objective: In this study we aimed to evaluate prognostic factors for the survival of patients with Fournier’s gangrene (FG), and overview different validated scoring systems for outcome prediction.

 

Material and methods: We retrospectively analyzed the data of 39 patients treated for FG in our clinic. Data were collected on medical history, symptoms, physical examination findings, vital signs, laboratory parameters at admission and at the end of treatment, timing and extent of surgical debridement, and the antibiotic treatment used. The Fournier’s Gangrene Severity Index (FGSI) and Charlson Comorbidity Index (CCI) were used to predict outcome. The data were analyzed in relation with the survival of the patients. Mann-Whitney U test, chi -square test, Wilcoxon signed rank test, and Cox regression analysis were used for the statistical analysis.

 

Results: Of 39 patients analyzed, 8 (20.5%) died and 31 (79.5%) survived. The median FGSI score on admission was 2 (0-9) for the survivors and 6 (2-14) for the non-survivors (p=0.004). The median CCI scores of the survivors and non-survivors were 2 (0-10) and 6.5 (5-11), respectively (p=0.001). Except for urea, albumin and hematocrit levels, no significant differences were found between survivors and non-survivors for other laboratory parameters on admission. Lower albumin levels and advanced age were found to be associated with mortality.

 

Conclusion: High blood urea, low albumin, and low hematocrit levels were associated with poor prognosis. High CCI and FGSI scores could be associated with a poor prognosis in patients with FG.

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EISSN 2980-1478