Turkish Journal of Urology
ENDOUROLOGY - Original Article

Effects of flexible ureteroscopy on kidney: A prospective clinical trial

1.

Department of Urology, Bağcılar Training and Research Hospital, İstanbul, Turkey

2.

Department of Biochemistry, Bağcılar Training and Research Hospital, İstanbul, Turkey

3.

Department of Urology, Van Training and Research Hospital, Van, Turkey

Turk J Urol 2020; 46: 297-302
DOI: 10.5152/tud.2020.19195
Read: 175 Downloads: 41 Published: 11 March 2020

Objective: To investigate the effects of flexible ureteroscopy (F-URS) on the operated side of a kidney by assessing the renal damage markers, urine neutrophil gelatinase-related lipocalin (NGAL) and serum cystatin-C (Cys-C), and overall kidney function with the measurements of standard serum creatinine and urine albumin and protein levels.

Material and methods: A total of 30 patients who underwent F-URS for treatment of upper urinary stone disease were prospectively evaluated. Preoperative serum urea, creatinine, and Cys-C levels were noted. Levels of urine albumin, protein, creatinine, and NGAL in spot urine samples from the operated side of a kidney obtained through the access sheath preoperatively and through the ureteral catheter 1 and 24 hours postoperatively were also measured. Preoperative and postoperative parameter levels were statistically compared.

Results: The patients’ mean age was 46.6±15.9 years. The mean operative and fluoroscopy times were 90.67±32.5 and 3.15±1.43 minutes, respectively. The urine creatinine, albumin, protein, albumin/creatinine, and protein/creatinine levels were similar in preoperative and postoperative periods. Postoperative serum urea, creatinine, and Cys-C levels and urine NGAL and NGAL/creatinine levels were not also found with remarkable changes from the baseline levels.

Conclusion: F-URS is a safe therapeutic intervention in the treatment of urolithiasis, especially regarding renal damage, and functional outcomes.

Cite this article as: Ertaş K, Temiz MZ, Çolakerol A, Küçük SH, Şahan A, Yürük E. Effects of flexible ureteroscopy on kidney: A prospective clinical trial. Turk J Urol 2020; 46(4): 297-302.

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ISSN2149-3235 EISSN 2149-3057