ISSN 2149-3235 | E-ISSN 2149-3057
Invited Review
Alternative therapies in patients with non-muscle invasive bladder cancer
1 Department of Urology, İstanbul University İstanbul School of Medicine, İstanbul, Turkey  
2 Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, USA  
Turk J Urol 2017; 43: 414-424
DOI: 10.5152/tud.2017.64624
Key Words: BCG; bladder cancer; instillation; survival

Bladder cancer (BC) is one of the leading causes of cancer-related deaths worldwide. Despite, the majority of the cases were diagnosed as non-muscle invasive bladder cancer (NMIBC) with favorable prognosis, it has tendency to recur or progress to a higher grade or stage. The first line treatment of patients with NMIBC is transurethral resection with adjuvant therapies primarily intravesical Bacillus Calmette-Guérin (BCG) immunotherapy. However, in a portion of patients whose BCG treatment failed, alternative treatments may be required. Furthermore, intravesical BCG may be contraindicated in or untolerated by a group of patients. For these patients, some treatment options are readily available and a variety of them are currently under clinical investigation. In this review, these alternative therapies have been summarized.



Cite this article as: Şanlı Ö, Lotan Y. Alternative therapies in patients with non-muscle invasive bladder cancer. Turk J Urol 2017; 43(4): 414-24.

Key Words
AVES | Copyright © 2018 Turkish Association of Urology | Latest Update: 08.10.2018