ISSN 2149-3235 | E-ISSN 2149-3057
Original Article
Preliminary feasibility study of a new method of hypothermia in an experimental canine model
1 Department of Urology, Necmettin Erbakan University Meram School of Medicine, Konya, Turkey  
2 Department of Urology, Selçuk University School of Medicine, Konya, Turkey  
3 Department of Surgery, Selçuk University School of Veterinary Medicine, Konya, Turkey  
4 Clinic of Urology, Gaziantep State Hospital, Gaziantep, Turkey  
Turk J Urol 2017; 43: 330-336
DOI: 10.5152/tud.2017.26878
Key Words: Hypothermia, partial nephrectomy, renal surgery, thermo-electric system
Abstract

Objective: To build up a new microcontroller thermoelectric system to achieve renal hypothermia.

 

Material and methods: Renal hypothermia system was tested under in vivo conditions in the kidneys of ten Mongrel dogs. Ambient temperature was evaluated using two different microcontrollers. In order to ensure hypothermia in the renal parenchyma, selection can be made among 4 modules and sensors which detect the temperature of the area. The temperature range of the system was adjusted between -50°C and +50°C.

 

Results: When single and double poles of the kidney were cooled, initial mean intraperitoneal temperature values were found 37.7°C for rectum and 36.5°C for renal cortex and medulla. After the temperature of the cooling module was set to 12°C, the module was placed on the poles of the kidney. After fifteen minutes, temperature was 15.4°C in the lower pole of the kidney, 28.1°C in the cortex of the other side and 29.2°C in the intramedullary region. The temperature was found to be 15°C in the vicinity and 26.1°C in the cortex across the module. After the system was stabilized, a very slight change was observed in the temperature.

 

Conclusion: Hypothermia system developed ensured desired cooling of the targeted part of the kidney; however, it did not cause a change in the temperature of other parts of the kidney or general body temperature. Thus, it was possible to create a long-term study area for renal parenchymal surgery.

 

Cite this article as: Sert İÜ, Akand M, Kılıç Ö, Yavru N, Bulut E. Preliminary feasibility study of a new method of hypothermia in an experimental canine model. Turk J Urol 2017; 43: 330-6

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