ISSN 2149-3235 | E-ISSN 2149-3057
Original Article
Evaluation of early and late period infections after renal transplantation: Clinical experiences of Sanko University Medical Faculty Transplantation Center
1 Department of Urology, Sanko University School of Medicine, Gaziantep, Turkey  
2 Department of Infectious Diseases, Sanko University School of Medicine, Gaziantep, Turkey  
3 Department of Emergency Medicine, Biruni University School of Medicine, Istanbul, Turkey  
4 Department of Transplantation Center, Sanko University School of Medicine, Gaziantep, Turkey  
Turk J Urol ; : -
DOI: 10.5152/tud.2018.09522
Key Words: Transplantation, renal, infections, early and late period
Abstract

 

Objective: Infections play an important part in post transplantation causes of morbidity and mortality. The purpose of this study is to evaluate the early and late period infections encountered in after renal transplantations.

 

Material and methods: 213 cases that consisted from both living and cadaver donors, who suffered from late period renal insufficiency and who had renal transplant between 2011-2016 at the Transplantation Center of Sanko University School of Medicine were included in the study. In this study the early and late period infections seen in post renal transplantation were examined retrospectively. Infection types, frequency and periods of infection, infection agents and predisposing factors were determined as the examination parameters.

 

Results: Of the 213 patients who received renal transplant, 139 were males (65.3%) and 74 were women (34.75%) and the average age was 42±11,8 (range, 14-70). The number of patients who were exitus after renal transplantation were 12 (5.6%). Post transplant infections were seen in 49 patients (23.1%) within 1-6 months; in 13 patients (6.1%) within 6-12 months; and in 5 patients (2.4%) after the 12th month. The most common infections after renal transplantation were associated with urinary tract (70 patients, 34.3%). The most frequent isolated agents were E.coli (66 patients, 30.9%), Kebsiella spp. (18 patients, 8.4%) and Enterococci (18 patients, 8.4%) respectively. The renal transplants from the cadavers were observed to have 1.78 times more infection compared to the living donors (OR=1.78, 95% CI=1.03-3.09).

 

Conclusion: The most common complication after renal transplantation are infections. The majority of the infections are seen within the first year especially between 1-6 months. Post transplant infections are often related to urinary system. E.coli was the most frequent isolated agent and it may be responsible for urosepsis in renal transplant patients.Infection more often seen in renal transplants from cadavers.

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